Classic complement early component deficiency
Classic complement early component deficiency
Definition
A genetic deficiency of any early component of the classical pathway (C1q, C1r/s, C2, C4, and C3) that is associated with autoimmune diseases due to the failure of clearance of immune complexes (IC) and apoptotic materials, and the impairment of normal humoral response.
Also known as genetic deficiency of early component of the classical complement pathway — per MONDO