Anal Paget disease
Anal Paget disease
Definition
A slowly spreading, erythematous eczematoid plaque in the anal region. Histologically, the basal part or whole thickness of the squamous epithelium is infiltrated by large cells with abundant pale cytoplasm and large nuclei. Half of the cases are associated with an internal malignancy, most often a colorectal adenocarcinoma. The other half of the cases, have a high local recurrence rate and they may become invasive (WHO).
Also known as anal Paget disease, anal Paget's disease, anus mammary Paget's disease, anus Paget disease, Paget disease of the anus, Paget's disease of anus, Paget's disease of the anus — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Alimentary part of gastrointestinal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Anus | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Anus | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Large intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |