Anal verrucous carcinoma
Anal verrucous carcinoma
Definition
A large, well differentiated squamous cell carcinoma with a cauliflower-like appearance, characterized by the presence of an exophytic and endophytic growth pattern. Morphologically, there is papillomatosis and acanthosis present, however cytologically the neoplastic squamous cells have a benign appearance. Dysplastic changes are minimal. It does not respond to conservative treatment and it is regarded by many authors as an intermediate lesion between condyloma acuminatum and squamous cell carcinoma.
Also known as anal Buschke-Lowenstein tumor, anal Buschke-Lowenstein tumour, anal giant (malignant) condyloma, anal verrucous carcinoma — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Alimentary part of gastrointestinal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Anus | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Anus | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Large intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |