Congenital fibrosarcoma
Congenital fibrosarcoma
Definition
A fibrosarcoma that occurs in infants. It shares identical morphologic features with adult fibrosarcoma but carries the t(12;15)(p13;q25) translocation that results in ETV6-NTRK3 gene fusion. It usually affects the superficial and deep soft tissues of the extremities. The prognosis is generally much more favorable than for adult fibrosarcoma, and it rarely metastasizes.
Also known as congenital fibrosarcoma, infantile fibrosarcoma, infantile fibrosarcoma (congenital fibrosarcoma), infantile fibrosarcoma (morphologic abnormality) — per MONDO