Intestinal disaccharidase deficiency

Intestinal disaccharidase deficiency

Definition

Inherited or acquired disorders of sugar metabolism. Deficiencies of lactase, maltase or sucrase-isomaltase usually occur irreversibly and independent of one another. Congenital deficiencies are rare whereas acquired deficiencies are more common and may be seen following intestinal mucosal brush-border injury. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following dietary intake of lactose, maltose or sucrose. The clinical course leads to malabsorption of disaccharides which has implications for normal growth and development if manifested at an early age.

Also known as intestinal disaccharidase deficiency and disaccharide malabsorption — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0