Pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma

Definition

An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are usually over 50 years of age. Microscopically it is characterized by the presence of glandular (ductal) differentiation and desmoplastic stroma formation. Signs and symptoms include pain, loss of weight, and jaundice. It grows rapidly and is usually detected after it has metastasized to other anatomic sites. The prognosis is usually poor.

Also known as ductal adenocarcinoma of pancreas, ductal adenocarcinoma of the pancreas, pancreas ductal adenocarcinoma, pancreas tubular adenocarcinoma, pancreatic duct adenocarcinoma, pancreatic ductal adenocarcinoma, pancreatic ductal carcinoma, pancreatic tubular adenocarcinoma — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Exocrine pancreas Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Pancreas Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Pancreas Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Ventral pancreatic duct Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Gemcitabine may treat MEDRT · Public domain (U.S. Government work)