Blast phase chronic myelogenous leukemia, BCR-ABL1 positive

Definition

An advanced phase of chronic myelogenous leukemia. It is characterized by: 1. the presence of blasts in the peripheral blood or bone marrow that are at least 20% of the peripheral blood white cells or of the nucleated cells in the bone marrow respectively, or 2. an extramedullary proliferation of blasts, and/or 3. when there are large aggregates and clusters of blasts in the bone marrow biopsy specimen (adapted from WHO, 2001).

Also known as blast crisis, blast phase chronic granulocytic leukaemia, blast phase chronic granulocytic leukemia, blast phase chronic myelocytic leukaemia, blast phase chronic myelocytic leukemia, blast phase chronic myelogenous leukaemia, blast phase chronic myelogenous leukemia, blast phase chronic myeloid leukaemia, blast phase chronic myeloid leukemia, blast phase CML, blastic phase chronic granulocytic leukaemia, blastic phase chronic granulocytic leukemia, blastic phase chronic myelocytic leukaemia, blastic phase chronic myelocytic leukemia, blastic phase chronic myelogenous leukaemia, blastic phase chronic myelogenous leukemia, blastic phase chronic myeloid leukaemia, blastic phase chronic myeloid leukemia, blastic phase CML — per MONDO

Also identified as

• MESH D001752 per MONDO
• NCIT C9110 per MONDO
• SCTID 413656006 per MONDO
• UMLS C0005699 per MONDO

Affected Organs

Drugs indicated