Gastric mucosa-associated lymphoid tissue lymphoma

Gastric mucosa-associated lymphoid tissue lymphoma

Definition

A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.

Also known as gastric MALT lymphoma, gastric MALToma, gastric mucosa-associated lymphoid tissue lymphoma, MALT lymphoma of stomach, MALT lymphoma of the stomach, MALToma of stomach, MALToma of the stomach, primary gastric B-cell MALT lymphoma, primary gastric MALT lymphoma, primary MALT lymphoma of stomach, primary MALT lymphoma of the stomach, stomach MALT lymphoma — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Lymphoid system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Stomach Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Stomach Disease Has Primary Anatomic Site NCIT · CC BY 4.0