Leydig cell tumor

Definition

A sex cord-stromal tumor occurring in the testis and rarely in the ovary. It is predominantly or completely composed of Leydig cells which may contain crystals of Reinke. In males it usually presents as a painless testicular enlargement and it may be associated with gynecomastia and decreased libido. The majority of the cases have a benign clinical course. Approximately 10% of the cases have a malignant clinical course and metastasize. In females it may be associated with androgenic manifestations and it follows a benign clinical course.

Also known as interstitial cell neoplasm, interstitial cell tumor, interstitial cell tumour, Leydig cell neoplasm, Leydig cell tumor — per MONDO

Also identified as

• DOID 2696 per MONDO
• MESH D007984 per MONDO
• NCIT C3188 per MONDO
• UMLS C0023601 per MONDO

Affected Organs