Primary cutaneous diffuse large B-cell lymphoma, Leg type
Primary cutaneous diffuse large B-cell lymphoma, Leg type
Definition
An aggressive primary cutaneous B-cell lymphoma, usually involving the lower leg. It is composed of a generally monotonous proliferation of immunoblasts, or less frequently centroblasts, with few admixed reactive cells. This type of lymphoma occurs most often in elderly women who present with rapidly growing tumors, usually on one or both legs. Dissemination to extracutaneous sites is frequent. Treatment with combination chemotherapy is usually required.
Also known as PCDLBCL,LT, primary cutaneous diffuse large B-cell lymphoma, Leg type — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Integumental system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Lymphoid system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Skin of body | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Skin of body | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |