Uveal melanoma

Definition

A melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B.

Also known as intraocular melanoma, melanoma (disease) of uvea, melanoma of the uvea, melanoma of uvea, melanoma, uveal, malignant, uvea melanoma, uvea melanoma (disease), uveal melanoma — per MONDO

Also identified as

• DOID 6039 per MONDO
• MESH C536494 per MONDO
• NCIT C7712 per MONDO
• OMIM 155720 per MONDO
• Orphanet 39044 per MONDO
• UMLS C0220633 per MONDO

Affected Organs