Necrobiosis lipoidica

Definition

Necrobiosis lipoidica is a rare skin disorder of collagen degeneration. It is characterized by a rash that occurs on the lower legs. It is more common in women, and there are usually several spots. They are slightly raised shiny red-brown patches. The centers are often yellowish and may develop open sores that are slow to heal. Infections can occur but are uncommon. Some patients have itching, pain, or abnormal sensations. It usually occurs more often in people with diabetes, in people with a family history of diabetes or a tendency to get diabetes, but can occur in nondiabetic people. About 11% to 65% of patients with necrobiosis lipoidica also have diabetes, but the exact cause is still not known. Treatment is difficult. The disease is typically chronic with variable progression and scarring.

Also known as necrobiosis lipoidica — per MONDO

Also identified as

• DOID 3486 per MONDO
• MESH D009335 per MONDO
• NCIT C34840 per MONDO
• Orphanet 542592 per MONDO
• SCTID 9418005 per MONDO
• UMLS C0027538 per MONDO

Affected Organs