Cerebral cavernous malformation

Cerebral cavernous malformation

Definition

A disorder characterized by malformations in the structure of the capillaries in the brain. It is caused by mutations in the CCM2, KRIT1 and PDCD10 genes. The capillaries fill with blood and stretch, thereby creating cavernous spaces. Some patients experience headaches, seizures, or visual and hearing disturbances. Cerebral hemorrhage may also occur.

Also known as brain cavernous hemangioma, CCM, cerebral cavernous malformation — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Cardiovascular system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Cardiovascular system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0