Maturity-onset diabetes of the young type 2
Maturity-onset diabetes of the young type 2
Definition
Monogenic diabetes caused by inactivating mutation(s) in the GCK gene, encoding glucokinase. Heterozygous GCK mutations may manifest as mild hyperglycemia, which is not progressive, and usually requires no treatment. Homozygous GCK mutations result in permanent neonatal diabetes.
Also known as GCK maturity-onset diabetes of the young (disease), GCK-associated diabetes mellitus, glucokinase-associated diabetes mellitus, maturity onset diabetes of the Young, type 2, maturity-onset diabetes of the young (disease) caused by mutation in GCK, MODY 2 monogenic diabetes type 2, MODY, type II, MODY2 — per MONDO
Also identified as
- DOID 0111100 per MONDO
- NCIT C129741 per MONDO
- OMIM 125851 per MONDO
- SCTID 237604008 per MONDO
- UMLS C0342277 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Alimentary part of gastrointestinal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Endocrine gland | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Pancreas | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Pancreas | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |