Guillain-Barre syndrome, familial
Guillain-Barre syndrome, familial
Definition
A form of Guillain-Barre syndrome (GBS) that occurs in persons or families with a genetic predisposition to the acute or chronic forms of GBS. Note that GBS is considered to be a complex multifactorial disorder with both genetic and environmental factors, and families with clear Mendelian inheritance have been rarely reported: a mutation in the PMP22 gene (601097) on chromosome 17 was identified in a single family with the acute (AIDP) and chronic (CIDP) forms of inflammatory demyelinating polyneuropathy.
Also known as AIDP, Guillain-Barre syndrome, familial, neuropathy, inflammatory demyelinating, polyneuropathy, inflammatory demyelinating, acute — per MONDO