Holt-Oram syndrome

Definition

Holt-Oram syndrome (HOS) is the most common form of heart-hand syndrome and is characterized by skeletal abnormalities of the upper limbs and mild-to-severe congenital cardiac defects.

Also known as atriodigital dysplasia type 1, heart-hand syndrome type 1, Holt Oram Syndrome, HOLT-Oram syndrome, HOS — per MONDO

Also identified as

• DOID 0060468 per MONDO
• ICD9 759.89 per MONDO
• MESH C535326 per MONDO
• NCIT C125592 per MONDO
• OMIM 142900 per MONDO
• Orphanet 392 per MONDO
• SCTID 19092004 per MONDO
• UMLS C0265264 per MONDO