Familial partial lipodystrophy, Dunnigan type
Familial partial lipodystrophy, Dunnigan type
Definition
Familial Partial lipodystrophy, Dunnigan type (FPLD2) is a rare form of genetic lipodystrophy characterized by a loss of subcutaneous adipose tissue from the trunk, buttocks and limbs; fat accumulation in the neck, face, axillary and pelvic regions; muscular hypertrophy; and usually associated with metabolic complications such as insulin resistance, diabetes mellitus, dyslipidemia and liver steatosis.
Also known as Dunnigan syndrome, familial partial lipodystrophy type 2, FPLD2 — per MONDO