Bethlem myopathy
Bethlem myopathy
Definition
A usually autosomal dominant inherited movement disorder caused by mutations in the COL6A1, COL6A2, and COL6A3 genes. It is characterized by progressive muscle weakness and joint stiffness in the fingers, wrists, elbows, and ankles.
Also known as benign autosomal dominant myopathy, Bethlem myopathy type 1 — per MONDO
Also identified as
- DOID 0050663 per MONDO
- MESH C535436 per MONDO
- NCIT C126688 per MONDO
- Orphanet 610 per MONDO
- SCTID 718572004 per MONDO
- UMLS C1834674 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Musculature | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculature | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |