Thrombophilia due to activated protein C resistance

Definition

A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

Also known as thrombophilia 2 due to activated protein C resistance, thrombophilia due to activated protein C resistance — per MONDO

Also identified as

• DOID 0111902 per MONDO
• ICD9 289.81 per MONDO
• MESH D020016 per MONDO
• OMIM 188055 per MONDO
• SCTID 421527008 per MONDO
• UMLS C1861171 per MONDO