DOORS syndrome
DOORS syndrome
Definition
DOORS syndrome (also known as DOOR syndrome) is a multiple congenital anomalies-intellectual disability syndrome characterized by sensorineural hearing loss (deafness), onychodystrophy, osteodystrophy, mild to profound intellectual disability, and seizures. Isolated seizure disorders and isolated hearing loss have also been reported in individuals as a proposed spectrum of DOORS syndrome.
Also known as autosomal recessive deafness-onychodystrophy syndrome, deafness-onychodystrophy-osteodystrophy-intellectual disability syndrome, deafness-onychodystrophy-osteodystrophy-intellectual disability-seizures syndrome, deafness-onychoosteodystrophy-intellectual disability syndrome, door syndrome, DOORS syndrome — per MONDO