Laron syndrome
Laron syndrome
Definition
Laron syndrome is a congenital disorder characterized by marked short stature associated with normal or high serum growth hormone (GH) and low serum insulin-like growth factor-1 (IGF-I) levels which fail to rise after exogenous GH administration.
Also known as complete growth hormone insensitivity, GH receptor deficiency, Growth Hormone Insensitivity, Growth hormone receptor deficiency, Laron syndrome, Laron-type dwarfism, primary GH insensitivity, primary GH resistance, primary growth hormone insensitivity, primary growth hormone resistance, short stature due to growth hormone resistance — per MONDO