Synovial sarcoma

Definition

Synovial sarcoma is an aggressive soft tissue sarcoma, occurring most commonly in adolescents and young adults (15 to 40 years), usually localized near the large joints of the extremities but also in the head and neck, mediastinum and viscera (lung, kidney etc), clinically presenting as a deep seated swelling or a painful mass often with an initial indolent course and is characterized by its local invasiveness and a propensity to metastasize. The origin of synovial sarcoma is likely from multipotent mesenchymal cells and not synovium (contrary to its name).

Also known as sarcoma, synovial, malignant, synovial sarcoma, synovial sarcoma (disease), Synovialosarcoma — per MONDO

Also identified as

• DOID 5485 per MONDO
• ICD9 171.9 per MONDO
• MESH D013584 per MONDO
• NCIT C3400 per MONDO
• OMIM 300813 per MONDO
• Orphanet 3273 per MONDO
• SCTID 302851001 per MONDO
• UMLS C0039101 per MONDO

Drugs indicated