Celiac disease

ICD-10 Code K90.0
Category Digestive

Celiac disease

Definition

An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet.

Also known as celiac disease, celiac sprue, coeliac sprue, gluten intolerance, gluten-induced enteropathy, non tropical sprue — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Alimentary part of gastrointestinal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Alimentary part of gastrointestinal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Small intestine Disease Has Primary Anatomic Site NCIT · CC BY 4.0