Capillary infantile hemangioma

Definition

Capillary hemangiomas are benign, highly proliferative lesions involving aberrant localized growth of capillary endothelium. They are the most common tumor of infancy, occurring in up to 10% of all births. Hemangiomas tend to appear shortly after birth and show rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers of mast cells. This phase is followed by slow involution at a rate of about 10% per year and replacement by fibrofatty stroma. Hemangiomas are classified as distinct from vascular malformations, in that the latter are present from birth, tend to grow with the individual, do not regress, and show normal rates of endothelial cell turnover.

Also known as HCI, hemangioma, capillary infantile, hemangioma, capillary infantile, somatic, hemangioma, hereditary capillary, hereditary capillary infantile hemangioma — per MONDO

Also identified as

• MESH C535860 per MONDO
• NCIT C6645 per MONDO
• OMIM 602089 per MONDO
• Orphanet 464293 per MONDO
• Orphanet 91415 per MONDO
• UMLS C1865871 per MONDO

Affected Organs