Monomelic amyotrophy

Monomelic amyotrophy

Definition

Monomelic amyotrophy (MA) is a rare benign lower motor neuron disorder characterized by muscular weakness and wasting in the distal upper extremities during adolescence followed by a spontaneous halt in progression and a stabilization of symptoms.

Also known as benign focal amyotrophy, Hirayama disease, JMADUE, juvenile muscular atrophy of distal upper extremity, juvenile muscular atrophy of the distal upper limb — per MONDO

Also identified as