MHC class I deficiency

MHC class I deficiency

Definition

Immunodeficiency by defective expression of HLA class 1 is a very rare, primary, genetic, immunodeficiency disorder characterized by partial or complete absence of human leukocyte antigen class I expression resulting in a non-specific clinical picture of impaired immune response and susceptibility to infections.

Also known as Bare lymphocyte syndrome type 1, immunodeficiency by defective expression of HLA class 1, immunodeficiency by defective expression of HLA class type 1 — per MONDO

Also identified as