Hereditary spastic paraplegia 19
Hereditary spastic paraplegia 19
Definition
Autosomal dominant spastic paraplegia type 19 is a pure form of hereditary spastic paraplegia characterized by a slowly progressive and relatively benign spastic paraplegia presenting in adulthood with spastic gait, lower limb hyperreflexia, extensor plantar responses, bladder dysfunction (urinary urgency and/or incontinence), and mild sensory and motor peripheral neuropathy.
Also known as autosomal dominant spastic paraplegia type 19, hereditary spastic paraplegia type 19, SPG19 — per MONDO