Myeloid neoplasm associated with FGFR1 rearrangement
Myeloid neoplasm associated with FGFR1 rearrangement
Definition
Hematologic neoplasms characterized by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients present with a myeloproliferative neoplasm, acute myeloid leukemia, lymphoblastic lymphoma/leukemia of T or B-cell lineage, or acute leukemia of mixed phenotype.
Also known as 8p11 myeloproliferative syndrome, 8p11 stem cell leukemia/lymphoma syndrome, 8p11 stem cell syndrome, chromosome 8p11 myeloproliferative syndrome, myeloid and lymphoid neoplasms associated with FGFR1 abnormalities, myeloid and lymphoid neoplasms with FGFR1 rearrangement, myeloid/lymphoid neoplasm associated with FGFR1 rearrangement, myeloid/lymphoid neoplasms with FGFR1 rearrangement, stem cell leukemia/lymphoma — per MONDO