Besifloxacin

ATC Code S01AE08

Besifloxacin

Definition

A synthetic fourth-generation fluoroquinolone antibiotic, with broad spectrum antibacterial activity. Upon administration, besifloxacin targets, binds to and inhibits both bacterial DNA gyrase, an enzyme essential for DNA replication, transcription and repair of bacterial DNA, and bacterial topoisomerase IV, an enzyme required for partitioning of the chromosomal DNA during bacterial cell division. This inhibits DNA replication, transcription, and repair and cell division.

Also known as (+)-7-((3R)-3-Aminohexahydro-1H-Azepin-1-yl)-8-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid, 3-Quinolinecarboxylic Acid, 7-((3R)-3-Aminohexahydro-1H-Azepin-1-yl)-8-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-, BESIFLOXACIN — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial conjunctivitis may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Conjunctiva may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Ocular adnexa may treat a disease of this organ DERIVED · CC BY 4.0

4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.