Suvorexant

Definition

An orally bioavailable antagonist of the orexin receptors orexin receptor type 1 (OX1R) and orexin receptor type 2 (OX2R), that can be used for the treatment of insomnia. Upon oral administration, suvorexant targets and binds to the orexin receptors OX1R and OX2R. This blocks the binding of the neuropeptides orexin-A and orexin-B to OX1R and OX2R, and prevents wakefulness that results from orexin signaling.

Also known as Belsomra, MK-4305, SUVOREXANT — per NCIT

Also identified as

• ATC N05CJ01 per RXNORM
• NCIT NCIT:C171858 per NCIT
• SCTID 708714001 per RXNORM
• SCTID 715609002 per RXNORM
• UNII 081L192FO9 per RXNORM

Indications