Idarucizumab

ATC Code V03AB37

Idarucizumab

Definition

A humanized monoclonal antibody fragment directed against the thrombin-binding site of dabigatran, that may be used as a specific reversal agent for dabigatran. Upon intravenous administration, idarucizumab binds to dabigatran and its acylglucuronide metabolites with a higher affinity than the binding affinity of dabigatran to thrombin, thereby neutralizing the anticoagulant effect of dabigatran.

Also known as BI 655075, BI-655075, BI655075, IDARUCIZUMAB, Praxbind — per NCIT

Also identified as