Netarsudil
Netarsudil
Definition
An amino-isoquinoline amide and inhibitor of Rho kinase (ROCK) and norepinephrine transporter (NET), with potential intraocular pressure (IOP)-lowering activity. Upon ocular administration, netarsudil inhibits ROCK and the Rho pathway, increases aqueous humor (AH) outflow via the trabecular pathway, and lowers IOP. In addition, netarsudil may lower IOP by decreasing episcleral venous pressure and decreasing the production of aqueous humor through inhibition of NET.
Also known as NETARSUDIL — per NCIT
Also identified as
- ATC S01EX05 per RXNORM
- NCIT NCIT:C170213 per NCIT
- SCTID 781253004 per RXNORM
- SCTID 781270007 per RXNORM
- UNII W6I5QDT7QI per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Ocular hypertension | may treat | MEDRT · Public domain (U.S. Government work) |
| Open-angle glaucoma | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.