Lidocaine (antiarrhythmic use)
Lidocaine (antiarrhythmic use)
Definition
A synthetic aminoethylamide with local anesthetic and antiarrhythmic properties. Lidocaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting the ionic fluxes required for the initiation and conduction of impulses and effecting local anesthesia.
Also known as .omega.-Diethylamino-2,6-dimethylacetanilide, 2-(Diethylamino)-2',6'-acetoxylidide, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide, 2-Diethylamino-2',6'-acetoxylidide, Cuivasil, Duncaine, Leostesin, LIDOCAINE, Lidothesin, Lignocaine, Omega-diethylamino-2,6-dimethylacetanilide, Rucaina — per NCIT
Also identified as
- ATC C01BB per NCIT
- ATC C05AD per NCIT
- ATC D04AB per NCIT
- ATC N01BB per NCIT
- ATC R02AD per NCIT
- ATC S01HA per NCIT
- ATC S02DA per NCIT
- NCIT NCIT:C614 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Esophageal disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Mouth disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Myocardial infarction | may treat | MEDRT · Public domain (U.S. Government work) |
| Ventricular fibrillation | may treat | MEDRT · Public domain (U.S. Government work) |
| Ventricular tachycardia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Heart | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculature | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Myocardium | may treat a disease of this organ | DERIVED · CC BY 4.0 |
5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.