Ranitidine

Definition

A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked.

NCIT:C29412 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as N-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine, RANITIDINE — per NCIT

Also identified as

ATC A02BA per NCIT
NCIT NCIT:C29412 per NCIT

Indications

Disease	Relation	Source
Duodenal ulcer	may prevent	MEDRT · Public domain (U.S. Government work)
Gastric ulcer	may prevent	MEDRT · Public domain (U.S. Government work)
Duodenal ulcer	may treat	MEDRT · Public domain (U.S. Government work)
Gastric ulcer	may treat	MEDRT · Public domain (U.S. Government work)
Gastroesophageal reflux disease	may treat	MEDRT · Public domain (U.S. Government work)
Peptic esophagitis	may treat	MEDRT · Public domain (U.S. Government work)
Zollinger-Ellison syndrome	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Alimentary part of gastrointestinal system	may treat a disease of this organ	DERIVED · CC BY 4.0
Esophagus	may treat a disease of this organ	DERIVED · CC BY 4.0
Intestine	may treat a disease of this organ	DERIVED · CC BY 4.0
Small intestine	may treat a disease of this organ	DERIVED · CC BY 4.0
Stomach	may treat a disease of this organ	DERIVED · CC BY 4.0
Upper digestive tract	may treat a disease of this organ	DERIVED · CC BY 4.0

6 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.