Famotidine
Famotidine
Definition
A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
Also known as FAMOTIDINE, Pepcid, Pepcid AC — per NCIT
Also identified as
- ATC A02BA per NCIT
- NCIT NCIT:C29045 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Duodenal ulcer | may prevent | MEDRT · Public domain (U.S. Government work) |
| Gastric ulcer | may prevent | MEDRT · Public domain (U.S. Government work) |
| Duodenal ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Dyspepsia | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastric ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastroesophageal reflux disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Helicobacter pylori infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Peptic esophagitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urticaria | may treat | MEDRT · Public domain (U.S. Government work) |
| Zollinger-Ellison syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Esophagus | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Small intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Stomach | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Upper digestive tract | may treat a disease of this organ | DERIVED · CC BY 4.0 |
7 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.