Omadacycline

ATC Code J01AA15

Omadacycline

Definition

An aminomethylcycline and a semisynthetic tetracycline derivative, with antimicrobial activity. Upon administration, omadacycline binds to the bacterial 30S ribosomal subunit and inhibits bacterial protein synthesis. Omadacycline is engineered to overcome certain tetracycline resistance mechanisms, including tetracycline-specific efflux pumps and ribosomal protection.

Also known as (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-9-{[(2,2-dimethylpropyl)amino]methyl}- 3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- carboxamide, 2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-(((2,2-dimethylpropyl)amino)methyl)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4s,4aS,5aR,12aS)-, 4-methylbenzenesulfonate (1:1), Amadacyclin, OMADACYCLINE, PTK 0796 — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial infectious disease may prevent MEDRT · Public domain (U.S. Government work)
Bacterial infectious disease may treat MEDRT · Public domain (U.S. Government work)
Bacterial pneumonia may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0

2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.