Sucralfate
Sucralfate
Definition
A nonabsorbable, aluminum salt of sucrose orasulfate with anti-ulcer, mucosa-protective and potentially anti-mucositis activity. Negatively charged sucralfate binds, through ionic bond formation, to positively charged proteins on mucosal surfaces, thereby creating a protective coating and physical barrier. This agent may also enhance the production of prostaglandin E2 locally, thereby promoting mucus production, increasing mucosal blood flow and stimulating epithelial proliferation and may contribute to the healing of damaged mucosa.
Also known as Carafate, SUCRALFATE — per NCIT
Also identified as
- ATC A02BX per NCIT
- NCIT NCIT:C848 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Duodenal ulcer | may prevent | MEDRT · Public domain (U.S. Government work) |
| Duodenal ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Esophagitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastric ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastritis | may treat | MEDRT · Public domain (U.S. Government work) |
| Pneumonia | may treat | MEDRT · Public domain (U.S. Government work) |
| Stomatitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Esophagus | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Small intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Stomach | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Upper digestive tract | may treat a disease of this organ | DERIVED · CC BY 4.0 |
9 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.