Prucalopride
ATC Code
A06AX05
Prucalopride
Definition
An orally bioavailable dihydro-benzofuran-carboxamide and selective serotonin (5-HT4) receptor agonist, with gastrointestinal (GI) prokinetic activity. Upon oral administration, prucalopride specifically targets, binds to and stimulates the 5-HT4 receptor. This alters colonic motility patterns and stimulates colonic mass movements. This may normalize bowel movements and may relief chronic constipation. In addition, by increasing esophageal and gastric motility, prucalopride may also provide relief for aspiration-associated symptoms.
Also known as PRUCALOPRIDE — per NCIT
Also identified as
- ATC A06AX05 per RXNORM
- NCIT NCIT:C74386 per NCIT
- SCTID 699273008 per RXNORM
- SCTID 774192009 per RXNORM
- UNII 0A09IUW5TP per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Constipation disorder | may treat | MEDRT · Public domain (U.S. Government work) |