Ubrogepant

ATC Code N02CD04

Ubrogepant

Definition

An orally bioavailable calcitonin gene-related peptide (CGRP) receptor antagonist that can be used in the acute treatment of migraines. Upon oral administration, ubrogepant targets, binds to and blocks the activity of CGRP receptor. This prevents CGRP-mediated signaling. By blocking the CGRP-mediated pathways, ubrogepant is able to ease migraine symptoms, especially migraine headache pain. CGRP-mediated signaling plays a key role in migraine pathogenesis.

Also known as MK-1602, Ubrelvy, UBROGEPANT — per NCIT

Also identified as

Indications

Disease Relation Source
Migraine may treat MEDRT · Public domain (U.S. Government work)
Migraine with aura may treat MEDRT · Public domain (U.S. Government work)
Migraine without aura may treat MEDRT · Public domain (U.S. Government work)