Cabotegravir

ATC Code J05AJ04

Cabotegravir

Definition

A human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), that is used for pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 infection. Upon gluteal intramuscular administration, cabotegravir binds to the active site of HIV integrase and inhibits the activity of HIV integrase, an HIV-1 coded enzyme that is necessary for viral replication. Inhibition of integrase prevents the integration of HIV-1 DNA into host genomic DNA.

Also known as Apretude, CABOTEGRAVIR — per NCIT

Also identified as

Indications

Disease Relation Source
HIV infectious disease may treat MEDRT · Public domain (U.S. Government work)