Rezafungin

Rezafungin

Definition

A next-generation, semi-synthetic, cyclic lipopeptide and echinocandin derivative, with potential antifungal activity. Upon administration, rezafungin inhibits the fungal specific enzyme 1,3-beta-D-glucan synthase, which is essential for fungal cell wall synthesis, and results in decreased synthesis of beta(1,3)-D-glucan. This weakens the fungal cell wall thereby causing osmotic lysis, fungal cell wall rupture and fungal cell death.

Also known as REZAFUNGIN — per NCIT

Also identified as

Indications

Disease Relation Source
Candidemia may treat MEDRT · Public domain (U.S. Government work)
Candidiasis, invasive may treat MEDRT · Public domain (U.S. Government work)