Nadofaragene Firadenovec

ATC Code L01XL10

Nadofaragene Firadenovec

Definition

A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, nadofaragene firadenovec infects nearby tumor cells and expresses INF alpha-2b intracellularly which activates the transcription and translation of genes whose products mediate antiviral, antiproliferative, antitumor, and immune-modulating effects.

Also known as Adstiladrin, Instiladrin, NADOFARAGENE FIRADENOVEC, Nadofaragene Firadenovec-vncg, Nadofaragene Firadenovec/Syn3, rAd-IFN, rAd-IFN-2b, rAd-IFN/Syn3, Recombinant Adenovirus-Interferon SCH 721015, Recombinant Adenovirus-Interferon With Syn3, Recombinant Adenovirus-Interferon/Syn3, SCH 721015, SCH-721015, SCH721015, TR 002, TR-002, TR002 — per NCIT

Also identified as