Imlunestrant

Imlunestrant

Definition

An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, imlunestrant specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that results in ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells. Imlunestrant is able to cross the blood-brain barrier (BBB).

Also known as IMLUNESTRANT, LY 3484356, LY-3484356, LY3484356, Selective Estrogen Receptor Degrader LY3484356, SERD LY3484356 — per NCIT

Also identified as

Indications

Disease Relation Source
Breast neoplasm may treat MEDRT · Public domain (U.S. Government work)