Lenalidomide
Lenalidomide
Definition
A thalidomide analog with potential antineoplastic activity. Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells.
Also known as 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione, CC 5013, CC-5013, CC5013, CDC 501, LENALIDOMIDE, Revlimid — per NCIT
Also identified as
- ATC L04AX per NCIT
- NCIT NCIT:C2668 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Mantle cell lymphoma | may treat | MEDRT · Public domain (U.S. Government work) |
| Multiple myeloma | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Lymphoid system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.