Mesalazine
Mesalazine
Definition
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04)
Also known as 5-Amino-2-hydroxybenzoic Acid, 5-Aminosalicylic Acid, 5-ASA, Apriso, Asacol, Lialda, MESALAMINE, Mesalazine, Pentasa, Rowasa — per NCIT
Also identified as
- ATC A07EC per NCIT
- NCIT NCIT:C29249 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Proctitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Sigmoid disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Ulcerative colitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Anus | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.