Carbamazepine
Carbamazepine
Definition
A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.
Also known as 5H-Dibenz(b,f)azepine-5-carboxamide, CARBAMAZEPINE, Epitol, Tegretol — per NCIT
Also identified as
- ATC N03AF per NCIT
- NCIT NCIT:C341 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Bipolar disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Complex partial epilepsy | may treat | MEDRT · Public domain (U.S. Government work) |
| Epilepsy with generalized tonic-clonic seizures | may treat | MEDRT · Public domain (U.S. Government work) |
| Post-traumatic stress disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Restless legs syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
| Substance withdrawal syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
| Trigeminal neuralgia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Brain | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.