Tigecycline

ATC Code J01AA12

Tigecycline

Definition

A broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This prevents the incorporation of amino acid residues into the elongating peptide chain, inhibiting protein synthesis and eventually bacterial cell growth.

Also known as TIGECYCLINE, Tygacil — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial infectious disease with sepsis may treat MEDRT · Public domain (U.S. Government work)
Bacterial pneumonia may treat MEDRT · Public domain (U.S. Government work)
Bacteroides infectious disease may treat MEDRT · Public domain (U.S. Government work)
Clostridium infectious disease may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Klebsiella infectious disease may treat MEDRT · Public domain (U.S. Government work)
Legionellosis may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0

2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.