Nitrofurantoin
ATC Code
J01XE01
Nitrofurantoin
Definition
A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04)
Also known as Macrobid, Macrodantin, NITROFURANTOIN — per NCIT
Also identified as
- ATC J01XE per NCIT
- NCIT NCIT:C29293 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Urinary tract infection | may prevent | MEDRT · Public domain (U.S. Government work) |
| Escherichia coli infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Klebsiella infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Staphylococcal infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |