Heparin
Heparin
Definition
A sulfur-rich glycosaminoglycan with anticoagulant property. Heparin binds to antithrombin III to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors, such as factors IX, X, XI, and XII, thereby preventing the polymerization of fibrinogen to fibrin and the subsequent formation of clots.
Also known as HEPARIN, UFH, Unfractionated Heparin — per NCIT
Also identified as
- ATC B01AB per NCIT
- ATC C05BA per NCIT
- ATC S01XA per NCIT
- NCIT NCIT:C539 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Pulmonary embolism | may prevent | MEDRT · Public domain (U.S. Government work) |
| Cerebral infarction | may treat | MEDRT · Public domain (U.S. Government work) |
| Coronary thrombosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Intermediate coronary syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
| Myocardial infarction | may treat | MEDRT · Public domain (U.S. Government work) |
| Pulmonary embolism | may treat | MEDRT · Public domain (U.S. Government work) |
| Thrombophlebitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Brain | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Heart | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculature | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Myocardium | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Vein | may treat a disease of this organ | DERIVED · CC BY 4.0 |
9 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.