Aminolevulinic Acid
Aminolevulinic Acid
Definition
A topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. (NCI04)
Also known as 5-ALA, 5-Amino-4-oxopentanoic Acid, 5-Aminolaevulinic Acid, 5-Aminolevulinic Acid, Amino-Levulinic Acid, AMINOLEVULINIC ACID, d-Amino-Levulinic Acid, Delta Aminolevulinic Acid, Delta-Aminolevulinic Acid — per NCIT
Also identified as
- ATC L01XD04 per RXNORM
- NCIT NCIT:C234 per NCIT
- SCTID 259496005 per RXNORM
- SCTID 409398000 per RXNORM
- UNII 88755TAZ87 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Actinic keratosis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.